Target fortification

Target fortification is used to tailor the maternal milk for the individual preterm infant’s nutritional needs by analysing the milk prior to fortification.

Miris helps you measure the macronutrient composition of human milk enabling individual nutrition for preterm infants.

The Dilemma

During the last trimester, the fetus has a growth rate that is three times greater than that of a term baby. The dilemma is that preterm babies are born with high energy requirements and low reserves of macronutrients. Furthermore, individual metabolic status, organ maturity and health can vary greatly. Because of this, one feeding regimen cannot be applied to all.

Large variation in breast milk

There are large variations in the macronutrient content of human milk used in neonatal care. Mother to mother variation, stage of lactation, and methods of storage and treatment can all affect composition.

The only way to be certain of macronutrient composition is to analyse. Miris Human Milk Analyzer provides the information that clinicians need to decide optimal macronutrient
composition to be given to each individual preterm infant.


The need to optimise nutrition

Although human milk boosts immunity it may not always meet the nutritional requirements of each individual. Miris Human Milk Analyzer helps develop individualised nutritional programmes that mimic intrauterine growth according to specific nutritional requirements of the three birth weight classes:  

The concentration of protein in human milk declines significantly after birth. The ESPGHAN 2010 guidelines2 indicate that most preterm babies have a protein deficit that is linked to their weight and composition of their feed.  Extreme and very low weight babies often need additional energy and protein to enable growth similar to intrauterin.



Target fortification. An interventional study.

Is targeted fortification of human breast milk an optimal nutrition strategy for preterm infants? An interventional study by L Morlacchi, D Mallardi, M L Giannì, P Roggero, O Amato, P Piemontese, D Consonni, and F Mosca, J Transl Med. 2016; 14:195.


Variability in human milk composition

Benefit of individualized fortification in very-low-birth-weight infants

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Miris HMA - Human Milk Analyzer gives the energy, fat, carbohydrate and protein content in human milk within minutes using a small sample volume.

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